HomeHealthZerodol SP Tablet: Uses, Side Effects, Price, Dosage, Composition and Substitutes

Zerodol SP Tablet: Uses, Side Effects, Price, Dosage, Composition and Substitutes

Zerodol SP tablet is used for inflammation, swelling, and relieving pain. It is a popular medicine given after surgery to the patients for pain relief. It is a combination of paracetamol, aceclofenac, and serratiopeptidase. 

Let us understand different details about the Zerodol SP in this section. We’ll go through its uses, composition, best dosage for adults, and price. You’ll get to know the possible Zerodol SP side effects and some alternative medications.

Zerodol SP tablet: Overview

Zerodol SP are manufactured by IPCA Laboratories Limited and are not only used for inflammation and swelling but also for quickening the healing process. Some of the common conditions treated by Zerodol are fever, inflammation, and swelling. 

Further, patients suffering from visceral pains, surgeries, infections, or trauma with mild to moderate conditions may use Zerodol SP. Hence, it is a commonly used drug in different mentioned conditions or medical issues.

Zerodol SP has paracetamol, aceclofenac, and serratiopeptidase combination and hence the following properties:

  • Zerodol SP comes under the category of NSAIDs (non-steroid anti-inflammatory drugs) due to the presence of aceclofenac
  • It has analgesic properties due to the presence of paracetamol and offers pain-relieving capabilities.
  • It has serratiopeptidase and hence comes under the category of proteolytic enzyme.

Zerodol SP Tablet Uses

After having a quick overview of Zerodol SP, below are the common uses of Zerodol SP tablet:

  • Pains in bones, gynae or reproductive health issues, and tooth pains
  • Helps in treating oedematic conditions
  • Aids in wound healing
  • Helps in mild and moderate visceral pains
  • Aids in treating injuries, surgeries, infections, fevers, joint pain, muscle pains, inflammation, and swelling

Zerodol SP Composition

After going through the different uses of Zerodol P tablets, it is easy to understand its composition of three different salts:

  • Serratiopeptidase IP 15 mg

It offers anti-oedemic, analgesic, and anti-inflammatory effects. It hydrolyses inflammatory mediators and decreases pain by inhibiting the pain-inducing amine. Further, it decreases the amount of fluid in tissues, allows fluid removal, and lowers oedema.

  • Paracetamol IP 325 mg

It has antipyretic and analgesic effects. Paracetamol inhibits the prostaglandin synthesis by blocking the pain impulse. Further, it acts on the hypothalamic heat regulation centre causing antipyretic effects. 

  • Aceclofenac IP 100 mg

It has analgesic and anti-inflammatory properties. Aceclofenac inhibits cyclooxygenase enzyme (COX) causing the conversion of arachidonic acid into prostaglandins. These are the chemical compounds causing fever, inflammation, and pain. 

Zerodol SP Dosage for Adults

While there is no data available for pediatrics about Zerodol SP dosage, it can be consumed by adults as one tablet daily. Below are some of the dosage guidelines for other people suffering from different abnormalities or under special conditions:

  • Geriatric patients

It is not recommended for patients suffering from GI disorder, or hepatic, and renal issues.

  • Renal impairment patients

It is contraindicated for patients suffering from renal patients.

  • Hepatic impairment patients

It is contraindicated for patients suffering from hepatic impairments.

  • Operating heavy machinery

People suffering from heavy machinery may not use the Zerodol P tablet due to vertigo, drowsiness, and dizziness problems.

  • Nursing women

Paracetamol is one of the components of this drug but some studies have shown the presence of paracetamol in breast milk. Hence, nursing women must consider the medical practitioner before using the Zerodol SP tablet.

  • Pregnancy

There are no confirmed studies to establish the use of Zerodol SP for pregnant women. However, it is recommended to take the help of the registered medical professional before starting to take Zerodol SP in pregnancy.

Precautions of Zerodol SP

Following are some of the precautions that people should follow while having Zerodol Sp:

  1. If you are a pregnant woman, you must take this medicine with the consideration of your doctor. 
  2. Do take this tablet if you are breastfeeding.
  3. Do not use any machine or do driving after having this tablet, as it causes dizziness. 
  4. If you are suffering from a serious disease like asthma, heart, kidney or liver problems or may be suffering from bleeding and ulcer in intestine, then it is advisable to consult with your doctor before having this medicine. 

Zerodol SP Tablet Price

Moving ahead, you may look for the price of the Zerodol P tablets. The maximum retail price or MRP of Zerodol SP is 118.30 INR for a single strip of ten tablets. It is available at almost every pharmacy shop, thanks to the distributed network by its manufacturers- IPCA Laboratories.

Zerodol SP Side Effects

It is essential to understand the side effects of Zerodol P tablets after going through their common uses. So, you must take care of the following side effects respective of its combinations:


  • Hypersensitivity
  • Anorexia
  • Vomiting
  • Diarrhea
  • Epistaxis
  • Rashes
  • Muscle or joint pains
  • Nausea
  • Abdominal discomfort
  • Haemoptysis
  • Cough


  • Severe allergic reaction
  • Decrease in the specific type of white blood cells or granulocytes
  • Formation of blood clots throughout the body
  • Skin rashes
  • Decreased oxygen-carrying capacity
  • An imbalance of phlegm, lymph, bile, and blood


  • Increased levels of hepatic enzymes
  • Dizziness
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Indigestion
  • Swelling due to the accumulation of excess fluid in the tissues
  • Spinning sensation due to a moving head
  • Anaemia due to death of the red blood cells
  • Decreased platelets count
  • Inflammation of the liver
  • Depression
  • Decreased neutrophile count
  • Decrease in the specific type of white blood cells

Zerodol SP Tablet Substitutes

Towards the end, you may look for the ideal solutions for the situations when you’re unable to get Zerodol P tablets due to any of the reasons. Following are the top Zerodol SP substitutes having the same composition and strength:

  • Acevah PS 100mg/ 325mg/ 15mg tablets manufactured by Abbott India Ltd
  • Nexonac SP tablets manufactured by Emenox Healthcare
  • Rexonac SP 100mg/ 325mg/ 15mg tablet manufactured by Rexion Healthcare Pvt Ltd
  • Seraheal tablet manufactured by IPCA Laboratories Ltd
  • Mahanac S tablet manufactured by Zuventus Healthcare Ltd
  • Vivian A Plus 100mg/ 325mg/ 15mg tablet manufactured by Lincoln Pharmaceuticals Ltd
  • Voltanec SP 100mg/ 325mg/ 15mg tablet manufactured by Cipla Ltd
  • Acecloren tablet manufactured by Indoco Remedies Ltd
  • Moviz-3D tablet manufactured by JB Chemicals and Pharmaceuticals Ltd
  • Signoflam tablet manufactured by Lupin Ltd

Wrapping Up

Hope everything is clear to you regarding Zerodol SP. We have mentioned details about its uses, side effects, price, dosage, composition, and substitutes. 

However, we strongly recommend you not to self-medicate as this article is intended for information purposes only. Always seek the expert help of a registered medical professional before starting to take any medicine.

Also, Read More About – Becosules Capsules

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